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Bobby Brown
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Bobby Brown   My Press Releases

You Will Lose It Before Your Know It

Published on 4/12/2019
For additional information  Click Here

Age-Related Muscle Loss Begins Before You Realize It

Quite often, people don’t recognize that they have lost muscle mass and function until they are 70 years old or older. This oversight is particularly the case with people who don’t participate in any organized recreational activities. They don’t experience a quantitative feedback on performance. The reason that it is not easy to recognize the problems caused by the loss of muscle mass and function is a phenomenon we call a “threshold effect.”

Here’s how it works: The loss of muscle starts in some people as early as age 30. By age 50, almost everyone is starting to lose a significant amount of muscle. However, you may not notice this because your body weight doesn’t change (or may even go up due to increased fat), and you can still comfortably perform the activities of daily living.
As the loss of muscle progresses, basic function may still be maintained, often until the onset of (an inevitable) health setback. The loss of muscle occurs even faster when there is serious illness, injury, or surgery. When the normal age-related rate of muscle loss is coupled with the accelerated loss that occurs in response to a health crisis, function may all of a sudden be affected to the point where you suddenly notice a problem—the “threshold” has been reached.

It’s Easier to Prevent Muscle Loss than to Regain Lost Muscle

Exercise is key to maintaining muscle mass as you age. However, after you have lost a significant amount of muscle, you become limited in the amount of exercise you are able to perform. Secondly, since the muscle has been depleted, there are metabolic changes that make it less receptive to the beneficial effects of essential amino acids. This is called anabolic resistance.

Anabolic Resistance

The metabolic basis for the loss of muscle with aging is that, over time, the rate of muscle protein breakdown exceeds the rate of muscle protein synthesis. What’s particularly interesting is that in the post-absorptive state (between meals), the rates of muscle protein synthesis and breakdown do not change with aging. But, when dietary protein is consumed there is a diminished increase in protein synthesis. In other words, normal protein nutrition is not as effective in the elderly as it is in younger people. The same amount of dietary protein elicits twice the stimulation of muscle protein synthesis in young individuals as it does in older, healthy individuals.
This dampened response is termed anabolic resistance and it is the principle reason why we lose muscle as we age. The situation is even more pronounced if an older person has some kind of physical stress. Even a case of the flu will make anabolic resistance worse, and more serious diseases like cancer take even more of a toil.


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