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Gene Hughes (MD)   My Press Releases

CBD | Heartburn | Acid Reflux | Dangers of Drugs | Side Effects

Published on 6/24/2019
For additional information  Click Here

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Heartburn or acid reflux is a symptom of GERD (Gastroesophageal Reflux Disease), which is a chronic digestive condition that bothers 15-30% of the adult population in the U.S., according to a 2014 study. In other words, nearly 3 out of 10 people are suffering from symptoms of acid reflux for extended periods of time, while it is estimated that all of us will experience symptoms of acid reflux at least once in our lifetimes.

The human gastrointestinal system is sensitive and complex. When the system is upset, it can produce acid reflux. That takes the form of mild heartburn or chronic even debilitating GERD (Gastroesophageal Reflux Disease). People often treat mild heartburn with over-the-counter medications or more serious conditions with prescribed pharmaceuticals. But, more people are using CBD Oil for acid reflux, something worth your consideration.

Here’s what happens...

A circle of muscle (sphincter) controls the entrance to the stomach. The Lower Esophageal Sphincter (LES) automatically closes after allowing food to pass through. If it fails to close or opens too often, the stomach’s natural hydrochloric acid will leak into the esophagus creating a sour taste and burning sensation in the throat.

Unlike the stomach, the esophagus has no protection against the acid. Many people feel this sensation after eating too fast or consuming greasy and acidic foods. About ten percent of Americans suffer from the more bothersome GERD which will damage the esophagus with its frequent and strong acid regurgitation.

A hiatal hernia may also cause acid reflux. It is a lesion in the diaphragm that lets the acid flow without control when the LES and stomach wind up above the diaphragm as in lying down after a big meal or internal pressures related to pregnancy.

It’s also common in those who are obese, smoke, and/or drink alcohol and coffee. Also, medications like aspirin, muscle relaxants, and blood pressure regulators can irritate the throat and stomach linings.

According to the Mayo Clinic, GERD may also produce a chronic cough, laryngitis, asthma, and sleep disturbance. And, the chronic condition may create scar tissue in the esophagus causing it to narrow making swallowing difficult. It can eat away at the delicate lining of the esophagus to produce a painful and bleeding ulcer. At worst, it will alter the lining tissue and risk the development of esophageal cancer.

How it is treated...

Patients use any number of commonly available medications and prescribed pharmaceuticals. People use antacids like Pepto Bismol, Rolaids, and Tums for fast relief. Even they have side effects like diarrhea or kidney damage.

Doctors may prescribe H-2 reception blockers like Axid AR, Pepcid AC, Tagamet HB, and Zantac. They take effect slower, but last longer than antacids. Side effects include constipation, diarrhea, drowsiness, fatigue, headache and muscle aches.

Proton pump inhibitors (PPI), including Prevacid 24 HR and Nexium, help heal esophageal tissue. They produce similar short-term side effects, but Harvard Health suggests researchers are concerned with the suppression of natural systems under long-term use. Researchers are looking into the remedies’ suppression of B-12 levels, association with pneumonia frequency, and correlation with the c. difficile infection.

Which leads us to our question:

Are Heartburn/Acid Reflux Drugs Really Safe?

The answer is that they are certainly not as safe as we wold like them to be, as numerous studies show. There are quite a few health risks lurking from the regular consumption of acid reflux drugs, especially PPIs...

  • Higher risk for stomach cancer - According to a study published by BMJ, PPIs were linked to a two times the risk of developing stomach cancer compared to a treatment with histamine-2 receptors antagonists (H2RAs) in patients who were taking either for an average period of 3-7 years. Additionally, the same study found that those who took PPIs on a daily basis were four times more likely to develop the disease compared to those that took PPIs on a weekly basis. Likewise, those who were taking PPIs for a period of more than a year had a higher risk of developing gastric cancer: Specifically, A five-to-eight times higher risk depending on duration of use.
  • Higher risk for kidney disease - 2009 study with 43,000 subjects has found that those who took PPIs had a 5.6% higher frequency of developing kidney problems compared to patients that only took H2RAs to reduce their symptoms. It also found that patients taking PPIs were more than 28 times more likely to develop chronic kidney disease, along with acute kidney injury and end-stage renal failure. Additionally, those taking PPIs were more prone to develop electrolyte imbalances. A newer 2017 study examining the use of PPIs like Prilosec and Nexium and their effect on kidney function in 125,000 patients showed that more than 50% of the patients that take PPIs and develop chronic kidney problems won’t experience clear and acute symptoms beforehand. Essentially, this means that the patient’s renal condition will worsen and they will not be aware of it. It is a gradual and “silent” progression of the disease of which doctors and patients should be more aware, especially when taking PPIs for longer periods of time.
  • Heightened risk of developing depression - Surprisingly, there is research to suggest a link between PPIs and depression. It is a well-known fact among scientists over the last decades that our mental health is not only affected directly from our brains but the function of our digestive system as well. People that lack a fair share of beneficial bacteria in their gut have a higher chance of developing mental health disorders like depression, anxiety and memory problems. An overrun of bad bacteria versus good bacteria discourages the release of certain neurotransmitters that affect our cognitive function. In an observational study with 2,366 test subjects, it was found that stomach acid medications like PPIs can negatively affect the gut-brain axis. More specifically the risk of developing clinical depression increased significantly in those who took the acid reflux drugs pantoprazole, rabeprazole and lansoprazole. The scientists of the study, commented that a possible explanation behind this negative link is that these drugs either intervene with the normal function of the gut and brain axis or the prevent the system from properly absorbing beneficial nutrients.
  • Increased stroke risk - Despite the fact that acid reflux drugs are frequently prescribed to reduce neck and chest pain as a symptom of GERD, a new study found that these should be used cautiously as they have the potential to increase the risk of an ischemic stroke. In this study with over 245,000 adult subjects, it was found that PPIs increase the risk of developing ischemic stroke by 21%. The study involved well-known PPI drugs like Prilosec and Protonix and a control group of subjects that did not take any of these drugs. These PPI drugs, according to the authors of the study, seem to cause vascular damage and raise the chances of a key artery getting blocked, leading to an ischemic stroke. Protonix, in particular, has been found to score the worst among other similar drugs, raising the chances of developing stroke by a whopping 94%!!! 

  • Heightened risk of developing liver disease - Researchers found in a 2017 study that. in addition to alcohol and other factors, PPIs appear to do their own part in causing liver damage. Through multiple experiments and observational studies in humans and mice, the researchers found that, since PPIs cause a reduction in gastric acid, bad bacteria like Enterococcus can multiply more easily and move from the intestines to the liver. They specifically found that the rate of liver disease was 8.3% higher in those who chronically consumed excess alcohol and took PPIs. The conclusion of the study was that our stomachs release gastric acid to kill consumed bacteria, and therefore taking drugs to decrease this natural stomach acid production may negatively change our gut’s bacterial balance, or what is termed our “microbiome.”
  • Increased risk for fractures in menopausal women - According to a clinical research with over 130,000 women between the ages of 50-79 years old, it was been shown that the women who took PPIs for long periods of time had 47% higher chances of suffering from spine fractures, 26% higher risk for forearm and wrist fractures and 25% raised risk for total fractures. Likewise, a Canadian 2008 study showed that the use of PPIs for a period of 5 years was linked to a 65% higher risk of developing hip fractures. Researchers aren’t sure what causes the link between PPIs and bone density, but their theory is that, by reducing stomach acid, nutrients like calcium and Vitamin D cannot be absorbed properly, resulting in bone problems.
  • Increased risk of asthma and allergies in babies - Acid reflux is one the most common symptoms of pregnancy due to the increased pressure in the intestines and changes in the digestive process. Several studies have found a link between pregnant women who take antacid drugs and a higher risk of the baby developing allergies and asthma. The researchers propose that this happens because PPIs may cross the cell membranes of the fetus and make it more sensitive to common allergens from food or the atmosphere.

  • Heightened risk of developing pneumonia - 

    In addition to the above health problems, there are also studies linking PPIs with hospital-acquired pneumonia. In one particular study, patients were four times more likely to contract pneumonia when taking PPIs as opposed to those who didn’t take any PPIs to treat their acid reflux symptoms. Researchers believe that the main reason why this happens is that antacids and lack of stomach acid can cause bad bacteria to multiply and make their way to the respiratory system, causing lung infections.

    If we examine all of the above negative side effects of PPIs, there are still many unknowns as to why these drugs are linked to disease. It seems clear that two main culprits may be:

    1. The proliferation of bad bacteria
    2. A decreased ability for the digestive system to absorb nutrients

 

So what can we do about this?
Speak with your doctor about the risks of PPIs . Clearly these drugs have major risks when used on a long-term basis, so the prospect of long-term use should be approached cautiously. If you’ve been taking PPIs, discuss with your doctor the possibility of transitioning off and introducing safer alternatives. If your condition is manageable through other means, such as gentler OTC solutions or home remedies, then that may be the way to go. Explore your options, discuss alternatives with your doctor and do your best to limit the use of drugs that could potentially do more harm than good.

References:

  1. https://medicine.wustl.edu/news/popular-heartburn-drugs-linked-higher-death-risk/
  2. https://www.healthline.com/health/gerd/facts-statistics-infographic#4
  3. https://www.bmj.com/company/newsroom/long-term-use-of-drugs-to-curb-acid-reflux-linked-to-doubling-in-stomach-cancer-risk/
  4. https://medicine.wustl.edu/news/popular-heartburn-drugs-linked-gradual-yet-silent-kidney-damage/
  5. https://www.medicalnewstoday.com/articles/314145.ph
  6. https://pediatrics.aappublications.org/content/pediatrics/early/2018/01/09/peds.2017-3741.full.pdf

[Buy CBD Online

CBD oil could be an option

Humans also have a complex and widespread Endocannabinoid System (ECS). It touches pain perception, memory, emotions, energy, musculature, neural transmission, and much more.

Of specific interest is its role in fighting gastric acid, relieving inflammation, and repairing mucosal damage.

Cannabis is known to match with the ECS repairing, rejuvenating, and restoring bodily tissues, muscles, and nerves. The CBD cannabinoid has anti-inflammatory effects to modulate the motility and volatility of intestinal propulsion. In its 2018 report by its Expert Committee on Drug Dependence, the World Health Organization (WHO) said...

“CBD is being actively explored for a range of indications consistent with its potential neuroprotective, antiepileptic, anxiolytic, antipsychotic, analgesic, anti-inflammatory, anti-asthmatic and antitumor properties.”

What CBD does is interact with the soft muscle tissue of the gastrointestinal system. It calms and soothes the peristalsis that moves food and waste. And, it modulates the LES to reduce spasms and irregular functions.

CBD also manages the secretion of hydrochloric acid. This decreases the likelihood of fluids sloshing around and splashing back into the esophagus. At the same time, it reduces inflammation and burning of the esophageal lining.

Studies have shown that CBD addresses multiple symptoms at once with little to no side effects. Cannabinoids change how the gut feels, it affects the signals the brain sends back and forth to the gut and regulates the functioning of the GI tract.

How safe is CBD oil?

Whenever people discuss new medications and/or therapies, one of the first issues to arise is how safe is it?

How safe is CBD oil? The answer is very safe. Initially, there were many stories and negative rumors concerning the safety issue surrounding cannabidiol. However, a report from the World Health Organization finally settled the issues at its 39th annual meeting. 

WHO stated once and for all that cannabidiol is “safe, well-tolerated and not associated with any significant adverse health effects.” This non-toxic cannabinoid will not be the cause of a failed drug test nor will it get you high.

In Conclusion...

CBD oil has been found to be a safe and effective product of the treatment of acid reflux disease with no long-term side effects. It is generally sold in small quantities, usually 1 oz. with an eye dropper to administer it orally by placing it under your tongue for about two to five minutes. It is also available in capsule form and as a cream or salve to use topically. However, sublingually (under your tongue) is the most efficient way. 10xPure CBD Oil has the highest absorption level (95%) you can buy, and is the most potent available.

I have been using it for over two years now and can tell you that it has helped my wife's acid reflux considerably and has helped my feet by erasing the pain of my Peripheral neuropathy symptoms...and more.

 

 [A DESCRIPTION OF YOUR IMAGE HERE

 [A DESCRIPTION OF YOUR IMAGE HERE

These statements have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure or prevent any disease. CTFO assumes no responsibility for the improper use of and self-diagnosis and/or treatment using these products. Our products should not be confused with prescription medicine and they should not be used as a substitute for medically supervised therapy. If you suspect you suffer from clinical deficiencies, consult a licensed, qualified medical doctor. You must be at least 18 years old to visit our website and make product purchases. We do not make any health claims about our products at CTFO. Before taking our products, it’s wise to check with your physician or medical doctor. It is especially important for people who are: pregnant, chronically ill, elderly, under 18, taking prescription or over the counter medicines. None of the information on our website is intended to be an enticement to purchase and may not be construed as medical advice or instruction. The use of any of our products for any reason, other than to increase general health and wellness, is neither, implied nor advocated by CTFO.

IMPORTANT NOTE: Almost all drug tests are designed to test for the presence of any Terpenes and/or Cannabinoids present in Marijuana (or Hemp.) They are NOT specifically testing for THC. This means that even with a true ZERO THC product like some of our products are, you can still test positive for a drug test. This is why we cannot guarantee any negative test results for people who are taking our products.

The information contained here is for general information and educational purposes only. It does not constitute medical advice. Therefore, any reliance you place on such information is strictly at your own risk. Please check with your medical doctor before starting or changing your CBD routine.

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