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posted on:
3/24/2012 12:23:55 PM EST
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Identifying the Genetic Risks (Type-2 Diabetes Part-4)
Beta3-Adrenergic Receptor Gene, diabetes management, diabetes medication, walk to cure diabetes
 VISIT WEBSITE (learn more)
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Hello: I take it that you have already read Parts 1, 2, and 3 of Type-2 Diabetes.
To read Part-1 go to www.ibosocial.com/zopsmgmt/blog.aspx?blogid=72374
To read Part-2 go to www.ibosocial.com/zopsmgmt/blog.aspx?blogid=73488
To read Part-3 go to www.ibosocial.com/zopsmgmt/blog.aspx?blogid=74560
If you've read Parts 1, 2, and 3 then you are in the right place. This is Part-4
Despite the problems outlined in Type-2 Diabetes series Parts 1 - 3, researchers have found a few gene mutations that influence diabetes risk in some families. One well studied gene is the Beta3-adrenergic receptor gene. For recent news about additional Type 2 diabetes genes, see related news below.
The Beta3-Adrenergic Receptor Gene
The Beta3-adrenergic receptor gene makes a protein in fat cells that is involved in determining how much fuel your body burns when you are resting. A mutation in this gene slows down how quickly a person burns fat — increasing their tendency to be obese. One specific mutation in this gene, called TRP64ARG, is almost four times more common in Pima Indians than in people of European descent, and is one and a half times more common in people of African or Mexican descent. The prevalence of the TRP64ARG gene mutation in these populations probably accounts at least in part for why these ethnic groups have a higher rate of Type 2 diabetes.
People with two copies of the TRP64ARG mutation have a slower metabolism than people without the mutation. Therefore, they tend to be more obese — even in mutation carriers who do not go on to develop diabetes. They also have a harder time losing weight than the general population. In addition, people with the TRP64ARG mutation develop diabetes at an earlier age than Type 2 diabetics without the mutation. This mutation is not present in all Type 2 diabetics, but it appears to change the course of diabetes in those who carry it.
The TRP64ARG mutation causes the Beta3-adrenergic receptor gene to make a different protein sequence. The name is an abbreviation for the change in the protein caused by the mutation. The altered protein has the amino acid Arginine (ARG) at the 64th position, rather than the amino acid Tryptophan (TRP). This switch in amino acid building blocks prevents the protein from working properly.
The Beta3-adrenergic receptor gene is not the only gene that regulates how we metabolize fat. Researchers think that mutations in similar genes may also put a person at risk for diabetes. So far, they have not found common mutations in these genes that cause diabetes, but there is ongoing research in high-risk populations and families to find additional gene mutations.
Genetic Testing
The genetics of Type 2 diabetes is complicated, with many different genes influencing a person's risk. Because of this array of genes, Type 2 diabetes is not inherited in a clearly dominant or recessive manner. Instead, a person may have one gene that increases their risk and other genes that decrease risk. Together, these genes, along with environmental factors, determine a person's overall risk for developing diabetes. With so many variables to consider, the medical community is a long way from a genetic test for Type 2 diabetes.
Although there is no genetic test for Type 2 diabetes, the American Diabetes Association recommends screening for diabetes onset every three years if you have diabetes in the family. Doctors screen for diabetes onset using a fasting glucose test or glucose tolerance test, which tells doctors if your blood glucose levels are unusually high.
If you know you are genetically at risk of becoming diabetic, be preventive and start taking Sweet EZE, by Youngevity.
Youngevity’s Sweet EZE is formulated to nutritionally support the regulation of blood sugar levels.
Key benefits:
- Supports the control of blood sugar levels after carbohydrate and protein rich meals
- Enhances the body’s ability to efficiently use insulin and regulates glucose levels
- Modulates the sweet tooth and promotes the reduction of sugar cravings
It works – I am living proof!
For more information contact me at 301-861-0303 or to place an order visit my web site at www.ibourl.net/SweetEZE2ControlA1Cs
Or click on learn more link above to watch a informative video on the SweetEze Product. To read Part-5 and the final blog in this series go to www.ibosocial.com/zopsmgmt/blog.aspx?blogid=75909
Thank you, Zalee Harris.
SLENDER FX™ SWEET EZE™ - 120 CAPSULES (Item #21014)
by Youngevity (Price $27.50)
Slender Fx™ Sweet Eze™ contains chromium, vanadium, and supportive herbs to nutritionally assist the body with the regulation of blood sugar levels.* SUGGESTED USE: Take 1 capsule with each meal, or as directed by your healthcare professional.
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 | | Zalee, thank you for sharing this information. No one should take their health for granted. This is information that I'm sharing for others to benefit. |
| | |  | | So glad you are around as living proof Zalee. Twittering! |
| | |  | | Thanks for sharing. Tweeting |
| | |  | | Great Blog on Diabetes and your product. Many people are not aware of this and I believe it is very important for others to see. I'm sharing. |
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